Migori County is a county in the former Nyanza Province of southwestern Kenya. It is located in Southwestern Kenya and borders Homa Bay County (North), Kisii County (North E), Narok (South East), Tanzania (West and South) and Lake Victoria to the West. The county also borders Uganda via Migingo Island in Lake Victoria. The county is headquartered by Migori town, which is also its largest town. The Kenya National Census of 2019 indicated that Migori County had a population of 1,116,436 compared to 917, 170 in 2009 Census. Migori County is located in the sugar belt wetlands of Western Kenya and is mostly at the heart of the African tropics. However, the county enjoys a pleasant climate because of high altitude which modifies the climate alongside the cool breeze from Lake Victoria.

Demographically, Migori County is the most diverse region of Nyanza after Kisumu. The inhabitants include AbaSuba people, Joluo, Abakuria, Abagusii, Abaluhya, Somalis, Indians, Arabs, Agikuyu and Nubians.

The county is important to Kenya because of the significance of Isebania border post to the East African economy, the A-1 Kenya-Tanzania cuts the county in half, the place of Sony (South Nyanza) Sugar Company in the lives of over one hundred thousand households in Kenya, the influential role of Lake Victoria on food sustainability of Western region of Kenya, and its sizeable meat industry courtesy of the ranches in Kurialand and Suna West.

Migori town serves as in important link between Kenya and Tanzania and the second most viable commercial center in Luo-Nyanza after Kisumu. Other major towns in Migori county include Kehancha, Rongo, Awendo and Isebania in Kuria District.